Background Adjusted Alignment-Free Dissimilarity Measures Improve the Detection of Horizontal Gene Transfer
Horizontal gene transfer (HGT) plays an important role in the evolution of microbial organisms including bacteria.Alignment-free methods based on single genome compositional information have been used to detect HGT.Currently, Manhattan and Euclidean distances based on tetranucleotide frequencies are the BIO FATS OMEGA 3-6-9 most commonly used align