BACKGROUND ADJUSTED ALIGNMENT-FREE DISSIMILARITY MEASURES IMPROVE THE DETECTION OF HORIZONTAL GENE TRANSFER



Co-Targeting Prostate Cancer Epithelium and Bone Stroma by Human Osteonectin-Promoter-Mediated Suicide Gene Therapy Effectively Inhibits Androgen-Independent Prostate Cancer Growth.

Stromal-epithelial interaction has been shown to promote local tumor growth and distant metastasis.We sought to create a promising gene therapy approach that co-targets cancer and its supporting stromal cells for combating castration-resistant prostate tumors.Herein, we demonstrated that human osteonectin is overexpressed in the prostate cancer epi

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